- Stevens Johnson Syndrome
- Stevens-Johnson Syndrome Open the popup dialog
- Stevens-Johnson Syndrome (SJS) is a rare and serious condition of the skin and mucous membranes. It’s usually a response to medication that starts with flu-like symptoms, followed by a painful rash that spreads and blisters. Then the top layer of the affected skin dies, peels off and begins to heal after a few days.
- Stevens-Johnson syndrome is a medical emergency that usually requires hospitalization. Treatment focuses on eliminating the cause, caring for wounds, controlling pain, and minimizing complications as the skin grows back. It can take weeks or even months to heal.
- A more severe form of the disease is called toxic epidermal necrolysis (NET). It affects more than 30% of the skin surface and significant lesions of the mucous membranes. Stevens-Johnson syndrome Treatment in Hyderabad
Early signs of Stevens-Johnson syndrome may appear one to three days before a rash appears, including:
- Mouth and sore throat
- Burning eyes
- As the disease develops, other signs and symptoms include:
Unexplained generalized skin pain
A red or purple rash that spreads
Stevens-Johnson Syndrome is a rare and unpredictable disease. Your doctor may not be able to identify the exact cause, but the condition is usually caused by medication, infection, or both. You may react to the medicines while you are using them or for up to two weeks after you stop using them.
Medications that can cause Stevens-Johnson syndrome include:
- Anti-gout drugs like allopurinol
- Medicines to treat seizures and mental illness (anticonvulsants and antipsychotics)
- Antibacterial sulfonamides (including sulfasalazine)
- Nevirapine (Viramune, Viramune XR)
- Pain relievers such as acetaminophen (Tylenol, others), ibuprofen (Advil, Motrin IB, others), and naproxen sodium (Aleve)
Factors that increase your risk of developing Stevens-Johnson syndrome include:
- HIV infection. In people with HIV, the incidence of Stevens-Johnson syndrome is about 100 times higher than the general population.
- A weakened immune system The immune system can be compromised by organ transplants, HIV / AIDS, and autoimmune diseases.
- Cancer. People with cancer, especially blood cancer, are at increased risk for Stevens-Johnson syndrome.
- A History of Stevens-Johnson Syndrome. If you have had a drug-related form of this disease, there is a risk of it coming back if you use this medicine again.
- A family history of Stevens-Johnson syndrome. If an immediate family member has Stevens-Johnson syndrome, you may also be more likely to develop it. Stevens-Johnson syndrome Treatment in Hyderabad
Consider genetic testing before taking certain medications. United States. The Food and Drug Administration recommends screening people of Asian and South Asian ancestry for a genetic variation called HLA-B * 1502 before starting treatment.
If you’ve had this condition, avoid the medications that started it. If you have had Stevens-Johnson syndrome and your doctor has told you that it was caused by a medicine, you should avoid this medicine and others who like it. This is important to prevent recurrence, which is usually more serious than the first episode and can be fatal. Stevens-Johnson syndrome Treatment in Hyderabad
Your family members may also want to avoid this drug because some forms of the disease have a genetic risk factor.