Marfan’s syndrome is an inherited disease that affects connective tissue – the fibers that support and anchor your organs and other structures in your body. Marfan’s syndrome most commonly affects the heart, eyes, blood vessels, and the skeleton.
People with Marfan syndrome are usually tall and thin with disproportionate arms, legs, fingers, and toes. The damage caused by Marfan Syndrome can be light or severe. If your aorta – the large blood vessel that carries blood from your heart to the rest of your body – is affected, the disease can be fatal.
Treatment usually includes medication to keep your blood pressure low and to lower the pressure on your aorta. Regular monitoring to check the progress of the damage is critical. Many people with Marfan syndrome eventually need preventive surgery to repair the aorta. Marfan syndrome Treatment in Hyderabad
Unusually long fingers, which are common in Marfan syndrome
Finger length in Marfan syndrome Open the pop-up dialog Young woman who measured her arm length
Longer Arms in Marfan Syndrome Open the popup dialog
The signs and symptoms of Marfan Syndrome vary widely, even among members of the same family. Some people have mild effects; others develop life-threatening complications. In most cases, the disease tends to progress with age. Marfan syndrome Treatment in Hyderabad
Features of Marfan’s syndrome can include:
- Tall and slim construction
- Disproportionately long arms, legs and fingers
- A sternum that protrudes outward or tumbles inward
- A high, arched roof of the mouth and clenched teeth
- Breaths to the heart
- Extreme nearsightedness
- An unusually curved spine
- Flat foot
Marfan’s syndrome is caused by a defect in the gene that allows your body to make a protein that increases the elasticity and strength of connective tissue.
Most people with Marfan syndrome inherit the abnormal gene from a parent with the disorder. Every child from an affected parent has a 50 to 50 chance of inheriting the defective gene. About 25% of people with Marfan syndrome do not have the abnormal gene from either parent. In these cases a new mutation develops spontaneously.
Marfan syndrome affects men and women equally and affects all races and ethnicities. Because it is a genetic disorder, the biggest risk factor for Marfan syndrome is having a parent with the disorder. Marfan syndrome Treatment in Hyderabad