Hairy cell leukemia cells under the microscope
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Hairy cell leukemia is a rare, slow growing blood cancer in which your bone marrow makes too many B cells (lymphocytes), which are types of white blood cells that fight infection.
These excess B cells are abnormal and appear “hairy” under a microscope. As the number of leukemia cells increases, fewer healthy white blood cells, red blood cells and platelets are produced.
Hairy cell leukemia affects more men than women and is most common in middle-aged or older adults. Leukemia, hairy cell Treatment in Hyderabad
Some people have no signs or symptoms of hairy cell leukemia, but a blood test for another disease or condition can inadvertently reveal hairy cell leukemia. Leukemia, hairy cell Treatment in Hyderabad
In other cases, people with hairy cell leukemia have signs and symptoms that are common with a number of diseases and conditions, such as:
- A feeling of fullness in your stomach that can make it uncomfortable to eat more than a little at a time
- Easy bruising
- Recurring infections
It is not known what causes hairy cell leukemia.
Doctors know that cancer occurs when cells make mistakes (mutations) in their DNA. In hairy cell leukemia, mutations in DNA cause the stem cells in your bone marrow to make too many white blood cells that are not working properly. Doctors don’t know what causes DNA mutations that lead to hairy cell leukemia.
There are certain factors that can increase your risk of developing hairy cell leukemia. Not all research studies agree on which factors increase your risk of disease.
Some research shows that your risk for hairy cell leukemia depends on your:
Radiation exposure. People who are exposed to radiation, e.g. B. People who work on x-ray machines who do not wear appropriate protective equipment or who have received radiation therapy for cancer may be at greater risk of developing leukemia. Hair cells, but the evidence is inconclusive.
Exposure to chemicals. There are conflicting studies on the role of industrial and agrochemicals in the development of hairy cell leukemia.
Hairy cell leukemia progresses very slowly and sometimes remains stable for many years. Because of this, there are few complications of the disease.
If left untreated, hairy cell leukemia can displace healthy blood cells in the bone marrow, leading to serious complications such as:
- Infections. A reduced number of healthy white blood cells puts you at risk of infections that your body might otherwise fight off.
- Bleeding. A low platelet count will prevent your body from stopping bleeding once it starts. If you have a mildly low platelet count you may find that you bruise more easily. Very low platelet counts can lead to spontaneous bleeding from the nose or gums. Leukemia, hairy cell Treatment in Hyderabad