Idiopathic myelofibrosis  Treatment in Hyderabad

overview

Myelofibrosis is a rare type of bone marrow cancer that affects the normal production of blood cells in your body.

Myelofibrosis causes extensive scars in the bone marrow, leading to severe anemia, which can lead to weakness and fatigue. It can also cause low numbers of blood clotting cells called platelets, which increases the risk of bleeding. Myelofibrosis often causes an enlarged spleen.

Myelofibrosis is considered to be chronic leukemia – cancer that affects the hematopoietic tissues of the body. Myelofibrosis belongs to a group of conditions called myeloproliferative diseases. Idiopathic myelofibrosis Treatment in Nizamabad

symptoms

Myelofibrosis usually develops slowly. At a very early stage, many people have no signs or symptoms.

As the disruption to normal blood cell production increases, signs and symptoms may include:

The reasons

Myelofibrosis occurs when stem cells in the bone marrow develop changes (mutations) in their DNA. Stem cells can replicate and divide into several specialized cells that make up your blood – red blood cells, white blood cells, and platelets.

It is not known what causes genetic mutations in bone marrow stem cells.

When mutated blood stem cells replicate and divide, they pass the mutations on to new cells. As more and more of these mutant cells emerge, they begin to have serious effects on blood production. Idiopathic myelofibrosis Treatment in Nizamabad

Risk factors

Although the cause of myelofibrosis is often unknown, certain factors are known to increase your risk:

Complications

Complications that can result from myelofibrosis include:

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