- Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. This mutation can increase the risk of developing abnormal blood clots, mostly in your legs or lungs.
- Most people with factor V ailments never develop abnormal clots. But in people who do, these abnormal clots can lead to long-term health problems or be life-threatening.
- Both men and women can have factor V ailments. Women with the Factor V Leiden mutation may have an increased tendency to develop blood clots during pregnancy or while taking the hormone estrogen.
- If you have factor V Leiden and have developed blood clots, blood-thinning medications can lower the risk of developing additional blood clots and help you avoid potentially serious complications. Factor V Leiden treatment in Hyderabad
- The Factor V Leiden mutation itself does not cause symptoms. Because factor V Leiden has a risk of developing blood clots in your leg or lungs, the first indication that you have the disorder may be that you develop an abnormal blood clot.
- Some clots do no harm and go away on their own. Others can be life-threatening. The symptoms of a blood clot depend on the part of the body affected.
- A clot in a deep vein
This is known as deep vein thrombosis (DVT), which is most common in the legs. DVT cannot cause symptoms. When signs and symptoms appear, they can include:
When you have Factor V Leiden, you inherited one copy or, rarely, two copies of the defective gene. Inheriting a copy slightly increases the risk of developing blood clots. Inheriting two copies – one from each parent – significantly increases the risk of developing blood clots. Factor V Leiden treatment in Hyderabad
A family history of factor V Leiden increases your risk of inheriting the disease. The disorder is most common in people who are Caucasian and are of European descent.
People who have inherited Factor V Leiden from only one parent have a 5 percent chance of developing an abnormal blood clot by the age of 65. Some of the factors that increase this risk include:
- Two faulty genes. Inheriting the genetic mutation from both parents instead of just one can dramatically increase the risk of abnormal blood clots.
- Immobility. Long periods of immobility, such as Sitting on a long airplane flight, for example, can increase the risk of blood clots in your legs.
- Estrogens. Birth control pills, hormone replacement therapy, and pregnancy can all increase the risk of developing blood clots.
- Operations or injuries. Surgery or injuries such as fractures can increase the risk of abnormal blood clots.
Factor V Leiden can cause blood clots in the legs (deep vein thrombosis) and in the lungs (pulmonary embolism). These blood clots can be life threatening. Factor V Leiden treatment in Hyderabad