Acute myeloid leukemia (AML) is cancer of the blood and bone marrow – the spongy tissue in the bones where blood cells are made.
The word “acute” in acute myeloid leukemia indicates the rapid progression of the disease. This is known as myeloid leukemia (my-uh-LOHJ-uh-nus) because it affects a group of white blood cells called myeloid cells that usually develop into different types of mature blood cells, such as blood cells. Red, white blood cells. and platelets.
Acute myeloid leukemia is also known as acute myeloid leukemia, acute myeloid leukemia, acute granulocytic leukemia, and acute non-lymphocytic leukemia. Acute myelogenous leukemia Treatment in Hyderabad
The general signs and symptoms of the early stages of acute myeloid leukemia may mimic those of the flu or other more common illnesses.
The signs and symptoms of acute myeloid leukemia include:
- Bone pain
- Lethargy and fatigue
- shortness of breath
- Pale skin
- Frequent infections
- Easy bruising
- Unusual bleeding such as frequent nosebleeds and bleeding gums
Acute myeloid leukemia occurs when a bone marrow cell develops changes (mutations) in its genetic material or DNA. A cell’s DNA contains the instructions that tell a cell what to do. Normally, the DNA tells the cell to grow at a set rate and eventually die. In acute myeloid leukemia, mutations instruct the bone marrow cells to keep growing and dividing.
In this case, the production of blood cells gets out of control. The bone marrow produces immature cells that turn into leukemic white blood cells called myeloblasts. These abnormal cells cannot function properly and can build and displace healthy cells.
It’s unknown what causes the DNA mutations that lead to leukemia, but doctors have identified factors that increase the risk. Acute myelogenous leukemia Treatment in Hyderabad
Factors that can increase your risk of acute myeloid leukemia (AML) include:
- Increased age. The risk of acute myeloid leukemia increases with age. Acute myeloid leukemia is more common in adults aged 65 and over.
- Your gender: Men are more likely to develop acute myeloid leukemia than women.
- Previous cancer treatment. People who have received certain types of chemotherapy and radiation therapy may be at higher risk of developing AML.
- Radiation exposure. People who are exposed to high levels of radiation, such as survivors of a nuclear reactor accident, are at increased risk of developing AML.
- Exposure to hazardous chemicals. Exposure to certain chemicals, such as benzene, is linked to an increased risk of AML.
- Smoke. AML is linked to cigarette smoke, which contains benzene and other known cancer-causing chemicals.
- Other blood disorders. People with other blood disorders such as myelodysplasia, myelofibrosis, polycythemia, or thrombocythemia are at higher risk of developing AML.
- Genetic disorders. Certain genetic disorders, such as Down syndrome, are linked to an increased risk of AML. Acute myelogenous leukemia Treatment in Hyderabad